Use non-standard types of ads

We all know that web-savvy(eg. webmasters or people that use the Internet for so many years, and know all the standards, conventions and so on) users are ad-blind.

Banners like 468x280 have been on the Internet since it's creation. Even people who use the Internet vaguely or once a month, are kind of blind to these standard banners.

Instead, use vertical skyscrapers, or boxed ads. They have a much higher click rate. The AdSense team even published a list of their highest performing ad sizes:

336x280 large rectangle
300x250 inline rectangle
160x600 wide skyscraper

End note : I hope these advices help some people. All d Best friends...